The newest and smallest campus in Tuttlingen (c. 35,000 inhabitants) is located in an area of lush green countryside, commonly known as "Medical Valley", approximately 30 kilometres east of Villingen-Schwenningen and 60 kilometres east of Furtwangen. The town is built around the Honberg Hill, site of a ruined medieval fort, nowadays used as a picturesque location for festivals and concerts in summer. Tuttlingen is a world centre of medical equipment production, home to more than 300 surgical equipment companies, with 50% of the world's surgical equipment manufactured here.
The campus currently has one faculty - The Faculty of Industrial Technologies. HFU's youngest campus in Tuttlingen offers degrees powered by industry. Industry works hand-in-hand with the university to design courses and provide teaching staff. Case studies and assignments are often sourced directly from partner companies and students receive their practical experience on their doorstep in local companies.