In the medical technologies core area of research at the Furtwangen University Institute for Applied Research, interdisciplinary research in medicine and engineering is carried out in the following areas:

Innovative Ventilation Systems

Innovative ventilation systems allow doctors to predict patients' reactions to different therapy parameters. Furthermore, on request, the systems can indicate optimal ventilation settings based on a patient's pathology. Mathematic models enable the precise calculation of a patient's reactions using a vast variety of simulations that far exceed the replication of the mechanics of the human respiratory system. For more information, please visit our website.

CONTACT

Prof. Dr. rer. nat. Knut Möller
Faculty of Medical and Life Sciences
Deputy Head of Institute for Applied Research
Schwenningen Campus, Room C 3.06
Jacob-Kienzle-Straße 17
D-78054 Villingen-Schwenningen
Tel: +49 (0)7720 307-4390
Fax: +49 (0)7720 307-4725
Email: moe(at)hs-furtwangen.de

Molecular Diagnostics and Biomarkers

The focus of this area of research is the identification and development of biomarkers in personalized and predictive medicine, particularly for applications in molecular diagnostics, therapy control and therapy optimization. This includes potential markers of all types of biomolecules (DNA, RNA, proteins and metabolites) as well as aspects of pathobiochemistry and the systemic biology (data integration) with emphasis on (mi)RNA and metabolites. Methods employed include micro-arrays, nucleic acid sequencing and metabolomics (mass spectrometry).

Design, modification and principles of new analytical, diagnostic and therapeutic applications of nano-particles are a further area of focus.

In the area of lipid-carried cellular signal transmission for pathomechanisms, sphingolipid-carried mechanisms are also examined, using for example synthesis and the application of bioactive model compounds.

Current Projects

CONTACT

Prof. Dr. rer. nat. habil. Hans-Peter Deigner
Dean of Faculty of Medical and Life Sciences
Tel: +49 (0)7720 307-4757
Fax: +49 (0)7720 307-4725
Schwenningen Campus, Room B 206
Email: dei(at)hs-furtwangen.de

Statistics in Biology and Medicine

Nowadays statistical evaluation methods play a central role in the life sciences. The main reason for this is the technological advances in high-throughput biochemical analysis of intracellular processes, such as RNA/DNA Microarrays or Next Generation Sequencing which have revolutionized biological research and are the foundation for innovation in clinical medicine and industry. However, utilizing these data to improve our understanding of the living world and to develop useful applications in biotechnology and medicine remain separate and challenging propositions. This type of analysis results in huge amounts of raw data.

Since the 1990s, many hospitals have collected the data in patient data management systems (PDMS). All diagnoses and therapies for individual patients is entered and can be centrally-accessed by hospital medical staff such as doctors and carers. The ability to access patient information is also important for hospital administrative staff for planning and costing purposes.

The enormous amounts of data in these databanks can only be adequately evaluated and used by the hospitals by means of specially-developed bio-informational and bio-statistical methods. It is important to have reliable statistical methods which produce very little or no variance.

Current projects
MultiFlow
PATIENTS: Patient-specific clinical decision-making support systems for organ failure

CONTACT

Prof. Dr. Matthias Kohl
Faculty of Medical and Life Sciences
Dean of Studies Medical Diagnostic Technologies (MDT)
Tel: +49 (0)7720 307-4635
Fax: +49 (0)7720 307-4725
Schwenningen Campus, Room B 2.07
Email: kohl(at)hs-furtwangen.de

Microbiology and Hygiene

Microbiology is the science and study of micro-organisms, organisms which are invisible to the naked eye such as bacteria and fungii. Micro-organisms can be found in huge numbers almost everywhere. For human beings they can be deadly pathogens or vital symbionts. The following are currently the main research topics of the Microbiology and Hygiene AG at HFU:

  • symbiotic and pathogenic human microbe interaction, particularly in the area of digestive and skin microbiology
  • hygiene research in the workplace, the household and in body hygiene

The research projects focus on the isolation and identification of micro-organisms from many different sample types, the evaluation of the findings with respect to their importance for human health, and the development of measures for targeted manipulation of microbiota in the samples examined. 

The work group is also working with HFU biotechnological projects on the cultural and molecular-biological characterisation of microbe communities in fermentation plants.

Current projects

  • immENS
  • Bilateral R&D industrial cooperation in the area of "Microbiology and Hygiene"

CONTACT

Prof. Dr. rer. nat. Markus Egert
Faculty of Medical and Life Sciences
Vice-Dean for Academic Affairs, Dean of MTZ degree programme
Lecturer of Microbiology at the University of Forestry Rottenburg (since WS 2012/13)
Tel: +49 (0)7720 307-4554
Fax: +49 (0)7720 307-4725
Schwenningen Campus, Room N 11.02
Email: ege(at)hs-furtwangen.de

Tumour Biology

The development, growth and metastasis of tumours is controlled by complex interactions within the body. To examine the exact process, in vitro tissue models are used. The use of such models allows defined growth conditions to be simulated and individual processes in tumour growth to be researched. The 3-dimensional tissue models create conditions which are as realistic as possible.

Research focuses on the development of 3-D tumour tissue models and microfluid models to examine tumour-induced new building of cells and cell-related tumour processes.

Current Projects
 
3D-TuMiMo

CONTACT

Prof. Dr. rer. nat. habil. Margareta Müller
Dean of Faculty of Medical and Life Sciences
Tel: +49 (0)7720 307-4231
Fax: +49 (0)7720 307-4725
Schwenningen Campus, Room C 2.10
Email: muem(at)hs-furtwangen.de

Cardiovascular Engineering and Simulation

The focus and core of this work is the development of medical simulators specifically adapted to the particular requirements of cardiovascular engineering. Current simulators are the basis for new developments in the fields of cardiovascular and anaesthetic engineering, miniature bypass systems, and innovative ventilation systems. It serves as a platform for the development of software for medical devices and for the continuing technical training of doctors and medical staff. Further information is also available at http://www.cardiosim.de.

CONTACT

Prof. Dr. Gerd Haimerl
Faculty of Mechanical and medical Engineering
Vice-Dean for Academic Affairs, Dean of Studies Medical Engineering
Schwenningen Campus, Room C 3.05
Jacob Kienzle Str. 17
D-78054 Villingen-Schwenningen
Tel: +49 (0)7720 307-4379
Fax: +49 (0)7720 307-4207
Email: hai(at)hs-furtwangen.de

Exercise Medicine and Diagnostics

This research area looks at the health-supporting effect of physical activity and the development and optimisation of measurement methods to record and document the resulting physical adaptation processes. The target group of the scientific developments are healthy people and patients, e.g. for secondary prevention or rehabilitation through movement therapy. A further focus is the software-supported, algorithmic evaluation and analysis of the physical ability in all secondary aspects. Focus of the research here includes the development and examination of the appropriate information and motivation systems.

CONTACT

Prof. Dr. med. Kai Röcker
Faculty of Health, Safety, Society
Institute for Applied Health Promotion and Exercise Medicine (IfAG)
Tel: +49 (0)7723 920-2954
Furtwangen Campus, O Building, Room O 0.06
Email: kai.roecker(at)hs-furtwangen.de